Construction and Research of Machine Learning Model for Predicting Osteoporosis Risk

LIAN Hong-yu; SHEN Xiang; CHEN Guang-xin; GUO Wei; SUN Yue

doi:10.12263/newIT.2024.04.001

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Construction and Research of Machine Learning Model for Predicting Osteoporosis Risk

RESEARCH PAPER | 更新时间：2025-05-15

- Construction and Research of Machine Learning Model for Predicting Osteoporosis Risk
- New Generation of Information Technology Vol. 7, Issue 4, Pages: 1-5(2024)
- 作者机构：
  
  1.牡丹江医学院附属红旗医院，黑龙江牡丹江 157011
  2.牡丹江医学院第一临床医学院，黑龙江牡丹江 157011
  3.牡丹江医学院医学影像学院，黑龙江牡丹江 157011
  4.牡丹江医学院生命科学学院，黑龙江牡丹江 157011
- 作者简介：
- 基金信息：
- DOI：10.12263/newIT.2024.04.001
  CLC： TP181
- Published：15 April 2024
- 稿件说明：
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廉洪宇, 沈翔, 陈广新, 等. 骨质疏松风险预测机器学习模型构建与研究[J]. 新一代信息技术, 2024, 7(4): 01-05

LIAN Hong-yu, SHEN Xiang, CHEN Guang-xin, et al. Construction and Research of Machine Learning Model for Predicting Osteoporosis Risk[J]. New Generation of Information Technology, 2024, 7(4): 01-05
廉洪宇, 沈翔, 陈广新, 等. 骨质疏松风险预测机器学习模型构建与研究[J]. 新一代信息技术, 2024, 7(4): 01-05 DOI： 10.12263/newIT.2024.04.001.

LIAN Hong-yu, SHEN Xiang, CHEN Guang-xin, et al. Construction and Research of Machine Learning Model for Predicting Osteoporosis Risk[J]. New Generation of Information Technology, 2024, 7(4): 01-05 DOI： 10.12263/newIT.2024.04.001.

摘要

本研究旨在通过比较多种机器学习算法对骨质疏松症的预测性能，筛选出最优算法并识别关键风险因素，为骨质疏松症的精准预防和治疗提供支持。本研究采用了包括决策树、AdaBoost在内的多种机器学习算法构建骨质疏松症预测模型，并评估了各模型的性能，同时分析了模型对特征重要性的评估。XGBoost模型在所有评估指标中表现最优，包括最高的AUC、准确度、精确度和

得分。决策树和AdaBoost模型也显示出良好的性能。我们发现年龄是一个重要特征，部分模型倾向于重视这一特征，而忽略其他特征。实验数据集和构建模型的算法有待进一步扩充和优化。在骨质疏松症预测模型性能和风险因素识别方面，集成学习算法表现优异，显示出在骨质疏松症预测中的巨大潜力。

Abstract

By comparing the predictive performance of various machine learning algorithms for osteoporosis

this study aims to screen out the optimal algorithm and identify key risk factors

so as to provide support for the precise prevention and treatment of osteoporosis. In this study

a variety of machine learning algorithms including decision tree and AdaBoost are used to construct osteoporosis prediction models

and the performance of each model is evaluated

and the evaluation of the importance of features is analyzed. The XGBoost model performed best in all evaluation metrics

including the highest AUC

accuracy

precision and

scores. Decision tree and AdaBoost model also show good performance. We found that age is an important feature

and some models tend to value this feature and ignore other features. The experimental data set and the model building algorithm need to be further expanded and optimized.Ensemble learning algorithm has excellent performance in predicting osteoporosis model performance and risk factor identification

which shows great potential in predicting osteoporosis.

关键词

Keywords

references

KELSEY J L . Risk factors for osteoporosis and associated fractures [J ] . Public Health Reports , 1989 , 104 ( S1 ): 14 - 20 .

CLYNES M A , HARVEY N C , CURTIS E M , et al . The epidemiology of osteoporosis [J ] . British Medical Bulletin , 2020 , 133 ( 1 ): 105 - 117 .

EBELING P R , NGUYEN H H , ALEKSOVA J , et al . Secondary osteoporosis [J ] . Endocrine Reviews , 2022 , 43 ( 2 ): 240 - 313 .

WU X G , PARK S . A prediction model for osteoporosis risk using a machine-learning approach and its validation in a large cohort [J ] . Journal of Korean Medical Science , 2023 , 38 ( 21 ): e162 .

YAMAMOTO N , SUKEGAWA S , KITAMURA A , et al . Deep learning for osteoporosis classification using hip radiographs and patient clinical covariates [J ] . Biomolecules , 2020 , 10 ( 11 ): 1534 .

LIM H K , HA H I , PARK S Y , et al . Prediction of femoral osteoporosis using machine-learning analysis with radiomics features and abdomen-pelvic CT: A retrospective single center preliminary study [J ] . PloS One , 2021 , 16 ( 3 ): e0247330 .

KIM S K , YOO T K , OH E , et al . Osteoporosis risk prediction using machine learning and conventional methods [C ] // 2013 35th Annual International Conference of the IEEE Engineering in Medicine and Biology Society (EMBC) . Piscataway : IEEE , 2013 : 188 - 191 .

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MAHESH B . Machine learning algorithms: A review [J ] . International Journal of Science and Research (IJSR) , 2020 , 9 ( 1 ): 381 - 386 .

CARLEO G , CIRAC I , CRANMER K , et al . Machine learning and the physical sciences [J ] . Reviews of Modern Physics , 2019 , 91 ( 4 ): 045002 .

BADILLO S , BANFAI B , BIRZELE F , et al . An introduction to machine learning [J ] . Clinical Pharmacology and Therapeutics , 2020 , 107 ( 4 ): 871 - 885 .

张玉 , 张书超 , 董梁 , 等 . 中老年男性原发性骨质疏松患者骨折风险预测模型列线图的构建及应用 [J ] . 河北医药 , 2022 , 44 ( 18 ): 2743 - 2746, 2751 .

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